Jonathan Taylor erupted for 165 rushing yards on 25 carries and 50 receiving yards on two receptions, totaling 215 scrimmage yards as the Colts rallied to a 29-28 Week 2 win over Denver. He earned AFC Offensive Player of the Week and a FedEx Ground & Air nomination after a 43-yard catch helped fuel an 85-yard drive. A 68-yard fourth-quarter run sparked the comeback, and his 22.38 mph top speed highlighted his explosive burst.

Vikings place Aaron Jones Sr. on IR with a hamstring injury, forcing a backfield reshuffle as Jordan Mason steps into a featured role behind a revamped depth chart that includes Ty Chandler and rookie Zavier Scott. Desmond Ridder lands on Minnesota’s active roster to provide veteran QB depth behind Carson Wentz and Max Brosmer. Cam Akers joins the practice squad, a familiar name with coaching ties to Kevin O’Connell and Wes Phillips. The move slate reshapes Minnesota’s fantasy outlook at RB and QB for the coming weeks.

KC faces a steep climb after an 0-2 start, but playoff odds remain favorable. BetMGM clocks KC at about 65% to reach the postseason, while only about 11% of 0-2 teams have advanced since 2020. The Chargers now lead the AFC West, reshaping division odds as KC tries to rebound. Mahomes remains the engine, but Lamar Jackson shows elite efficiency and long field goals are surging across the league, adding new wrinkles for fantasy managers.

Buffalo’s 30-10 win over the Jets followed an opening victory against Baltimore, with bets heavily favoring Buffalo and the Bills maintaining a strong Super Bowl LX favorite stance. Detroit’s 52-21 demolition of Chicago underscored the Lions’ ceiling, while Philadelphia edged Kansas City in a Super Bowl rematch. Falcons, Buccaneers, and Chargers all earned wins in a NFL-dominated weekend. On the MLB side, Trey Yesavage’s major-league debut for Toronto sparked big multi-pick payouts as the Jays edged Tampa Bay.